CLR Error

[Chip]

I am using Outlook 2003. It has worked for several months fine but suddenly
started giving me the following message on startup:

"Could not intialize CLR. Required permissions cannot be aquired." The
banner says" Managed MAPI Service Catstrophic Failure"

I have reinstalled and repaired and still get the error message. I also
cannot get into my business contacts anymore.

Has anyone had a similar problem?

Thanks for any help or direction.