You could roll your own along the lines o
http://groups.google.com/group/microsoft.public.excel.worksheet.functions/msg/4c446fa2eb605d5b
The direct limit on MINVERSE is 52 columns (including the column of 1's for
the constant term), but unless your x columns are orthogonal, it is quite
likely that you would need much more than the available numeric precision to
get meaningful results, which is probably why LINEST has a much smaller
limit. For example
http://groups.google.com/group/microsoft.public.excel/msg/969a2bb33e6cdbb8
gives an example where trying to fit a 6th degree polynomial by these direct
matrix formulas would fail to give a single correct figure for any
coefficient, without more precision than is available in IEEE double
precision (used by Excel and almost all other general purpose software).
A freely downloadable statistics package that uses a better numeric
algorithm than direct matrix formulas is R, which is a dialect of the S
language
http://www.r-project.org
Jerry