Do you mean you want to perform some math operation on all the cells when you
input a number into one specific cell?
Assume number is entered in A1.
Assume range is B1:B100
In C1 enter =B1*$A$1 which will multiply by the number in A1
Double-click on fill handle of C1 to copy down.
Another method is to enter a number in an unused cell.
Copy that cell.
Select the range to change and Paste Special>Multiply>OK>Esc
Change the number and do it again.
Gord Dibben MS Excel MVP
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