You could create a workbook that has the settings you want. Then save
this workbook as a template for all new workbooks.
If that's what you want to do:
Start a new workbook.
change all the settings that you want--including the gridlines under
File|Page setup
for all the sheets in that workbook.
Also, modify anything else you want as a standard--header/footers, page
orientation, number of worksheets in that workbook???
Now save it as a template in your XLStart folder as book.xlt
Then when you click on that New icon, the new workbook will inherit all those
settings.
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If you create another file named sheet.xlt (in the same XLStart location), then
every new worksheet added will inherit the settings from this template.
I set up book.xlt the way I wanted it (one sheet only) and then used windows
explorer to copy it to sheet.xlt. Then they would be identical. (Seemed like
less work, too.)