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Message: [QUOTE="Chris Dudding, post: 3445347"] No, there aren't any macros of any kind in this spreadsheet. The formulas are intact when saving, but after its reopened about 1/3 of the formulas are gone. It follows a pattern: most of the missing formulas are on the bottom half of the spreadsheet - as if Excel stopped trying to save the formulas. We have duplicated this problem several times. It seems to stop once file size gets below 1.0GB. Unfortunately, this isn't possible with this most recent spreadsheet. perhaps deleting any rows or columns, as you cells on those deleted rows/columns. [/QUOTE]