There is no Out of Office Assistant in Entourage. You can set up the Out of
Office Assistant via Outlook Web Access if you're on an Exchange Server.
Otherwise, you can investigate to see if your mail provider offers an
auto-response feature.
If not, you can set up a rule in Entourage to reply to all messages.
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http://www.entourage.mvps.org/rules/example/rule003.html>
Make sure you read the requirements at the bottom.
Note that Out of Office is available in Entourage 2008.
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http://snipurl.com/1w5bs>