Outlook won't open after using it 2 times

[wja]

I've tried several different approaches, but each time I turn on the computer
I'm asked if I want to start in safe mode or not. If I do, then I get a
message that "Outlook Express" (which I don't use) is not my default email.
Then I get another window about subscribing to rss feeds, which I don't have.
After using Outlook 2 times I can no longer open it, regardless if I go safe
mode or not. I have Office 2007 Professional which was installed as an
ungrade from Office 2000. I tried to reinstall the Outlook from the disks,
but I was told I could only upgrade. If there is no solution to this problem,
should I take out 2007 altogether, reinstall 2000 and then put 2007 back on.
If I do go this route, then what happens to my email files?

 

[DL]

Have you created a new Profile, added a new data file, then the accounts &
tested them?
Create the new profile using the mail applet in the control panel