Unable to copy/paste in Excel once clipboard gets full

[Sean via OfficeKB.com]

Hi all,

I do a lot of copying/pasting in excel. This gets 'tossed' into the
Clipboard and somehow gets full. When this happens, I'm unable to copy/paste.
I close excel completely and am still unable to copy/paste. The weird thing
is that it affects other programs, not just Office. Is there a way to clear
the clipboard? Or is there something else that could be the cause? Thanks
for any feedback.

Sean