Change my code to. See below for an easy way to make automatic
Sub HiglightLargestFiveUnique() 'with helper columnn
Cells(1, "l").Value = Application.Max(Range("e2:e72"))
For i = 2 To 5
Cells(i, "l").FormulaArray = _
"=max(if(e2:e72<l" & i - 1 & ",e2:e72))"
Next i
Columns(5).Interior.ColorIndex = 0
On Error Resume Next
ci = 37
For Each cel In Range("l1:l5")
With Range("e2:e" & Cells(Rows.Count, "e").End(xlUp).Row) 'rng
Set c = .Find(cel, _
LookIn:=xlValues, lookat:=xlWhole)
If Not c Is Nothing Then
firstAddress = c.Address
Do
c.Interior.ColorIndex = ci
Set c = .FindNext(c)
Loop While Not c Is Nothing And c.Address <> firstAddress
End If
End With
ci = ci + 1
Next cel
End Sub
To autorun the macro on a change in col E (5)
Private Sub Worksheet_Change(ByVal Target As Range)
If Target.Column = 5 Then HiglightLargestFiveUnique
End Sub